Children in the UK will be the first in Europe to receive a life-changing treatment for peanut allergies, after NHS England secured a deal for a drug that decreases the severity of symptoms including anaphylaxis.
The oral treatment, Palforzia, will be available to up to 600 children aged four to 17 the first year and 2,000 the following year.
The news will help affected families as they navigate anxiety over everyday events like mealtimes, birthday parties and eating out, and carry adrenaline injections to treat anaphylaxis, a severe, potentially life-threatening allergic reaction. About one in 50 UK children suffer from peanut allergies.
The treatment stems from from two large peanut allergy clinical trials – the Palisade and Artemis studies – which the Evelina London children’s hospital took part in. Sophie Pratt, whose nine-year-old daughter, Emilia, took part in the trial, told PA Media it “had changed our whole family’s lives”.
“The treatment we received has meant that Emily is free from limits and the fear that the tiniest mistake could put her life at risk, and it has removed all the tension and worry that the simple act of eating loomed over us every day," lei disse
Since the trial, Emily had been able to attend parties with confidence, feed animals at the zoo and take her first holiday to New York, Pratt said.
The change “was particularly noticeable at special occasions like birthdays, Christmas and on holidays where there are often special foods like cakes, ice cream and treats that invariably had warnings, ‘may contain peanuts’ or menus not in English,” Pratt added.
An Imperial College London studia mal di testa, del 187 people who died from anaphylaxis in the UK from 1992 per 2018, almeno 86, o 46%, suffered from peanut or other nut allergies.
In the Artemis study, six in 10 children were able to eat a dose of peanut protein of 1,000mg – well above the accidental exposure amount – by the end of the trial, whereas previously they had reacted to 10mg.
Stephen Powis, national medical director of NHS Inghilterra, said the treatment would “reduce the fear and anxiety for patients and their families who may have been living with this allergy for years.
“This pioneering treatment can be life-changing for patients and their families and, thanks to the deal the NHS has struck, people here will be the first in Europe to benefit," Egli ha detto.
Powis added that families should be able to “enjoy meals out or holidays abroad together without worrying about an allergic reaction that could land them in hospital or worse”.
Former Liberal Democrat leader Jo Swinson, who has a nut allergy, had to be injected with adrenaline at Glasgow’s Southern General hospital in 2013 after eating a biscuit containing nuts. “It was a very scary experience," lei disse.
George du Toit, children’s allergy consultant at Evelina London and senior investigator on the UK trials, said Palforzia’s approval was a “significant step forward” and would “protect against accidental exposure to peanuts”.