A passenger train derailed in Missouri on Monday afternoon and initial reports said some people aboard were injured, Amtrak said.
The Southwest Chief was carrying about 243 passengers when it collided with a dump truck in Mendon at 1.42pm, Amtrak spokeswoman Kimberly Woods said.
The train was traveling from Chicago to Los Angeles.
Social media posts from the scene show several rail cars on their sides. The Missouri highway patrol said eight cars derailed.
Three passengers were being taken from the scene to University hospital in Columbia, hospital spokesman Eric Maze said. He did not have information on their conditions.
The highway patrol and other local law enforcement units were at the scene to help and Amtrak said it has deployed resources to the site.
Mendon, with a population of about 160, is about 84 miles north-east of Kansas City.